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	<title>Comments on: Deriving biological meaning from principal components analysis</title>
	<atom:link href="http://www.bioinformaticszen.com/2007/08/meaning-from-pca/feed/" rel="self" type="application/rss+xml" />
	<link>http://www.bioinformaticszen.com/2007/08/meaning-from-pca/</link>
	<description></description>
	<pubDate>Fri, 21 Nov 2008 20:13:28 +0000</pubDate>
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		<item>
		<title>By: ioni</title>
		<link>http://www.bioinformaticszen.com/2007/08/meaning-from-pca/#comment-22619</link>
		<dc:creator>ioni</dc:creator>
		<pubDate>Wed, 16 Jul 2008 06:39:50 +0000</pubDate>
		<guid isPermaLink="false">http://www.bioinformaticszen.com/feed/#comment-22619</guid>
		<description>Hi, 

Thank you. Found it very helpful including the R code.</description>
		<content:encoded><![CDATA[<p>Hi, </p>
<p>Thank you. Found it very helpful including the R code.</p>
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	<item>
		<title>By: Rewards, output and academia &#171; What You&#8217;re Doing Is Rather Desperate</title>
		<link>http://www.bioinformaticszen.com/2007/08/meaning-from-pca/#comment-12603</link>
		<dc:creator>Rewards, output and academia &#171; What You&#8217;re Doing Is Rather Desperate</dc:creator>
		<pubDate>Mon, 10 Mar 2008 06:50:59 +0000</pubDate>
		<guid isPermaLink="false">http://www.bioinformaticszen.com/feed/#comment-12603</guid>
		<description>[...] Deriving biological meaning from principal components analysis - by Mike [...]</description>
		<content:encoded><![CDATA[<p>[...] Deriving biological meaning from principal components analysis - by Mike [...]</p>
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	<item>
		<title>By: gamini.gunasekera</title>
		<link>http://www.bioinformaticszen.com/2007/08/meaning-from-pca/#comment-5392</link>
		<dc:creator>gamini.gunasekera</dc:creator>
		<pubDate>Sun, 18 Nov 2007 05:47:04 +0000</pubDate>
		<guid isPermaLink="false">http://www.bioinformaticszen.com/feed/#comment-5392</guid>
		<description>sir,       
        i have some idea  of PCA. Why do you need to reduce the dimensions in the data. 
would not stepwise multivatiate analysis be more usefl for interpretation of variation?

look forward to a helpful answer.

with to learn PCA. any good books and suggestions.

you essay was very useful to a beginner. afterall we must relate the components to the original data. 


thank you

gamini/ error in firt msg re name</description>
		<content:encoded><![CDATA[<p>sir,<br />
        i have some idea  of PCA. Why do you need to reduce the dimensions in the data.<br />
would not stepwise multivatiate analysis be more usefl for interpretation of variation?</p>
<p>look forward to a helpful answer.</p>
<p>with to learn PCA. any good books and suggestions.</p>
<p>you essay was very useful to a beginner. afterall we must relate the components to the original data. </p>
<p>thank you</p>
<p>gamini/ error in firt msg re name</p>
]]></content:encoded>
	</item>
	<item>
		<title>By: lydia</title>
		<link>http://www.bioinformaticszen.com/2007/08/meaning-from-pca/#comment-2784</link>
		<dc:creator>lydia</dc:creator>
		<pubDate>Sun, 16 Sep 2007 06:25:55 +0000</pubDate>
		<guid isPermaLink="false">http://www.bioinformaticszen.com/feed/#comment-2784</guid>
		<description>thanks a lot for the interpretation.</description>
		<content:encoded><![CDATA[<p>thanks a lot for the interpretation.</p>
]]></content:encoded>
	</item>
	<item>
		<title>By: Animesh Sharma</title>
		<link>http://www.bioinformaticszen.com/2007/08/meaning-from-pca/#comment-2015</link>
		<dc:creator>Animesh Sharma</dc:creator>
		<pubDate>Fri, 10 Aug 2007 13:32:55 +0000</pubDate>
		<guid isPermaLink="false">http://www.bioinformaticszen.com/feed/#comment-2015</guid>
		<description>Thanks Mike for this update, apart from PCA, I really learned a lot about plotting in R from this post :) .
Regarding PCA, I use to understand this just as a dimensionality reduction technique where components were ranked on the basis of their contribution towards the data's variance.
One suggestion in your code [ http://www.bioinformaticszen.com/wp-content/uploads/2007/07/pca_post.txt ], we need to do a 'find and replace' for the '/Users/mike/Desktop/post/' string to User's working directory before running the code in R [ source('pca_post.txt') ].</description>
		<content:encoded><![CDATA[<p>Thanks Mike for this update, apart from PCA, I really learned a lot about plotting in R from this post <img src='http://www.bioinformaticszen.com/wp-includes/images/smilies/icon_smile.gif' alt=':)' class='wp-smiley' /> .<br />
Regarding PCA, I use to understand this just as a dimensionality reduction technique where components were ranked on the basis of their contribution towards the data&#8217;s variance.<br />
One suggestion in your code [ <a href="http://www.bioinformaticszen.com/wp-content/uploads/2007/07/pca_post.txt" rel="nofollow">http://www.bioinformaticszen.com/wp-content/uploads/2007/07/pca_post.txt</a> ], we need to do a &#8216;find and replace&#8217; for the &#8216;/Users/mike/Desktop/post/&#8217; string to User&#8217;s working directory before running the code in R [ source('pca_post.txt') ].</p>
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	<item>
		<title>By: Bio::Blogs #13 &#171; What You&#8217;re Doing Is Rather Desperate</title>
		<link>http://www.bioinformaticszen.com/2007/08/meaning-from-pca/#comment-1833</link>
		<dc:creator>Bio::Blogs #13 &#171; What You&#8217;re Doing Is Rather Desperate</dc:creator>
		<pubDate>Fri, 03 Aug 2007 01:35:47 +0000</pubDate>
		<guid isPermaLink="false">http://www.bioinformaticszen.com/feed/#comment-1833</guid>
		<description>[...] up is Mike again with a detailed look at principal components analysis. This is a very useful multivariate statistical method which I&#8217;ve used a lot myself and he [...]</description>
		<content:encoded><![CDATA[<p>[...] up is Mike again with a detailed look at principal components analysis. This is a very useful multivariate statistical method which I&#8217;ve used a lot myself and he [...]</p>
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